Alabaster, not your regular or I say typical Tezuka Manga or Story.
As you have already read or seen Osamu Tezuka's other works like Astro Boy , Black Jack , Dororo, Buddha etc. You can grasp the magical world of aestheticism, science fiction and drama of his craftsmanship. But what makes Alabaster different from any regular stories of Tezuka is the framing of our anti-hero , Alabaster as the Hater of Beauty. As African-Amerian,James Block, being a professional sportsman, becomes the victim of racism. And this changes everything for him, he begin to hate his skin color. The story take a great turn of event when this unfortunate victim of rasicm meets an mad scientist in a jail and he gets to know his invention 'Invisible Ray Gun' by which any object can get invisible. Hating his skin color, he makes his mind to invisible himself but this decision backfires by leaving him to be half invisible; up to his outward skin, leaving his veins and skull visible. And abhorring his new gory look he generate a tendency toward hating anything beautiful. This gives birth to crime like mass murder, terrorism, animal cruelty and assassination.
Later, we get to meet a character called Ami, the granddaughter of that mad scientist, being raised by a lawyer. This kid is no ordinary kid but an result of a mad research in which her mother becomes the victim leaving her fully invisible to the core. And to live with this extraordinary power, she has to put on makeup like a clown and become the victim of bullying. She becomes the foil for Alabaster, suffering the same torture of society but having the different view to it's punishment.
Through Cosmic Conspiracy, they meet and commit the crime of murder and terrorism throughout the world. And they build an organization for these crimes.
Some may find this Manga as not par as Tezuka's another works but the characters like these are very few in the world of Tezuka. You can compare Alabaster to Black Jack and Hyakkimaru, they suffer the same pangs of society's term of 'irregular' or 'monster' but what differentiate Alabaster is his radicalism. As for me, I didn't hate the story but we have already have seen these kind of story very much everywhere. But still, I find it very interesting, the approach of Osamu Tezuka's view upon the creation of Anti-hero who loathes everything which discards him as irregular. I advice you to don't criticise this work just because you have already read or watched Astro boy or Dororo. This is a very different work with very criticised views. But I think you may, I repeat, you may find it interesting if you forget about other work and enjoy it one of Tezuka's brilliant works.